MEMS syringes offer possibilities of painlessly injecting suspensions of fine drug powders and biocompatible liquids through an array of hollow microneedles into the epidermis under the stratum corneum. The stratum corneum serves as the main barrier to transdermal penetration and drug delivery. It is important to find microneedle design parameters that will maximize skin penetration and delivery of drugs into the epidermal skin layer. Eventually, microneedles may be adapted for medical injection applications such as diabetes treatment and vaccines.
Project end date: 02/02/05