Liwei Lin (Advisor)

Implantable drug delivery devices that allow for remote, repeatable, and reliable drug delivery are expected to greatly improve the efficacy of medical treatments in the near future. However, few delivery systems to date have met the necessary requirements – sufficient drug storage, precision control over drug delivery, and on-demand activation – to be broadly useful. In this project, we develop an implantable drug delivery device that can be remotely controlled and provide drug on the on- demand basis for several years without replacement. We develop drug release mechanisms and...

Mechanical engineering methods and microfabrication techniques offer powerful means for solving biological challenges. In particular, microfabrication processes enable researchers to develop technologies at scales that are biologically relevant and advantageous for executing biochemical reactions. Here, microfluidic, optofluidic, an 3D printing-based methodologies are employed to develop autonomous microfluidic components, circuits, and systems for chemical and biological applications.

Project end date: 08/15/14

The project amis at using Near Field Electrospinnin to fabricate top gate graphene transistor that is capable to pattern the source and drain electrodes through a self-alignment process, and the long range goals is to direct writing graphene transistors onto flexible and transparent substrate for low cost circuit applications, say RF mixer. As the conventional top gated device fabrication process often introduces the deposition of thin inorganic dielectric onto graphene layer with extra surface functionalizations, leading to an undesired damage of graphene lattice, or a non-ideal...

Particulate-based vaccines offer a safer alternative to traditional organism-based vaccines; however, their effectiveness to provoke immune response largely depends on the micro/nano- delivery systems carrying the antigen. In this project, we introduce a new class of functional microcapsules that offer the potential to not only overcome a number of hurdles associated with current particulate vaccine manufacturing technology (e.g., exposure of antigens to organic solvents or degradation during encapsulation), but also enable new functionalities for transporting the microcapsules and...