LPL41: Raised Lateral Patch Clamp Array

We are developing a prototype capable of reproducing both the geometry and the function of the traditional glass micropipette tip on chip in a high density configuration. Our technology provides a novel high throughput platform for ion channel studies and is highly compatible with existing multiple-well plate format, allowing simple integration with robotic sample handling system. The device is fabricated on transparent polymer substrate PDMS, and thus allows easy integration with immunofluorescent assay platform to provides electrical and optical measurement concurrently.

Project end date: 02/07/06