Drug monitoring plays crucial roles in doping control and precision medicine. It helps physicians tailor drug dosage for optimal benefits, track patients’ compliance to prescriptions and understand the complex pharmacokinetics of drugs. Conventional drug tests rely on invasive blood draws. While urine and sweat are attractive alternative biofluids, the state-of-the-art methods require separate sample collection and processing steps and fail to provide real-time information. Here we present a wearable platform for drug monitoring. Both stationary iontophoretic induction and physical exercise are utilized as our methods of sweat extraction. Sweat drug levels are then monitored under various conditions, such as drug doses and measurement time after drug intake. Our work leverages a wearable sweat sensing platform towards noninvasive and continuous point-of-care drug monitoring and management.
Project end date: 08/10/20