Studies on blood parabiosis between young and old mice have shown reversals in the progression of aging. However, the definitive cellular elements in young mice that advance rejuvenation in old mice are yet to be identified. The goal of this project is to determine the specific blood component in young mice responsible for rejuvenation in old mice. This project focuses on designing a microfluidic-based blood exchange device capable of continuously separating and exchanging different type of blood components during blood transfusion between small animals to help identify the blood components responsible for rejuvenation.
Project end date: 01/31/17