Wearable sensors have attracted considerable interest in various fields, such as clinical diagnosis, environmental pollution monitoring and food quality assessment, due to their practical advantages of operation convenience, low cost and in-situ analysis mode. Among different sensing methods, electrochemical sensing is very popular due to its high efficiency and accuracy. Broadly speaking, there are two kinds of electrochemical biosensors: enzymatic and non-enzymatic sensors. Compared with enzymatic sensors, non-enzymatic sensors show enhanced stability, simplicity, reproducibility, and cost effectiveness. Among a variety of electrode materials for non-enzymatic wearable sensors, carbon textile is attractive because it is flexible, conductive, and stable in corrosive conditions. Furthermore, it provides large surface area, high porosity and a three- dimensional structure, which are crucial for sensitive nanostructure-based electrochemical devices. It is also inexpensive and biocompatible among carbon-based materials. However, proper surface functionalization is needed to achieve good selectivity for the detection of specific analytes. Herein, we are developing wearable non-enzymatic electrochemical sensors for the detection of different biomarkers in human fluid.
Project end date: 11/27/19