BPN838: Dosimetry Dust: An Implantable Dosimeter for Proton Beam Therapy Treatment of Ocular Melanomas

Abstract: 

Proton beam therapy is a well-established medical procedure for treating certain kinds of cancer, and is uniquely suited for treatment of head, neck, and eye tumors. In order to effectively treat a patient’s tumor, medical physicists have developed various simulations to model proton interactions with tissue and create a patient specific treatment plan that determines optimal gaze angles, the depth of penetration, and width of the spread-out-Bragg Peak necessary to encompass the target tumor. Despite the continuous improvements in medical physics treatment plan simulations, improper tissue irradiation can easily occur if there is a physical shift in the tumor and/or critical organs during the irradiation process (ex. patient movement). Currently, there are no micro-implantable feedback methods to assure proper irradiation of a tumor, and inform a physician what the in vivo dose is. We propose the use of a MOSFET silicon based radiation detector that employs ultrasonic power harvesting and backscatter communication through the use of a piezoelectric transducer.

Project end date: 09/05/17

Author: 
Stefanie V. Garcia
Publication date: 
August 21, 2017
Publication type: 
BSAC Project Materials (Final/Archive)
Citation: 
PREPUBLICATION DATA - ©University of California 2017

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