In this project we are striving to develop biocompatible passive micro-scale transducers which are able to measure transient extracellular ion concentrations and transmit them at microwave frequencies. We are interested in fabricating implantable MEMS devices which shift their resonant frequency whenever a nearby neuron fires. When implanted up to 2 mm deep into the brain cortex, we expect these devices to enable next-generation distributed neural interfaces featuring not only superior spatial and temporal resolution of extracellular action potentials but also robust long-term operation in vivo. This project has a broad scientific as well as social impact: It will enable advances in neural, cognitive and behavioral science by opening up a new window into the complexity of the brain. Additionally, it may lead to improved neural prosthetic devices ameliorating the quality of life for patients suffering from neurodegenerative diseases.
Project end date: 08/10/10