BPN615: Integrated Microfluidic CMOS (imCMOS) for Quantitative Cell Biology

We present an integrated microfluidic CMOS (imCMOS) system for high-accuracy cell adhesion analysis. The hybrid imCMOS system combining novel microelectronic and microfluidic technologies features a large array of capacitive sensors implemented in 90 nm CMOS process and incorporated with microfluidic processor for cell culture devices. This imCMOS method offers the advantages of real-time, quantitative, high precision and high throughput focal cell adhesion analysis suitable for a verity of applications including neural interface studies. We demonstrate the preliminary results of system design and implementation for the electrically assessment of neural cell-surface adhesion.

Project end date: 08/19/11