BPN384: Single-cell Analysis via Raman Spectroscopy


There has been significant interest in applying Raman Spectroscopy on cellular analysis in recent years. Advanced optics has allowed very high resolution Raman signal measurement at the sub-cellular level, fueling the emerging field of Single-cell Raman Spectroscopy. The fact that Raman Spectroscopy/Imaging is in few ways superior to conventional fluorescence techniques enables novel ways of monitoring cell processes. Recently, multiple studies have reported the use of Raman Spectroscopy methods in detecting specific cell behaviors. However, an extensive quantitative study has yet to be carried out to correlate and verify the Raman signature pattern with various cell processes. The goal of this project is to apply novel single-cell analysis techniques with Raman Spectroscopy methods to establish models that relate Raman measurement with cell behavior.

Project end date: 01/29/08

Publication date: 
August 15, 2007
Publication type: 
BSAC Project Materials (Final/Archive)
PREPUBLICATION DATA - ©University of California 2007

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