BPN412: Signal Amplifications of SERS by Microfluidic CD-based Preconcentration Methods

Signal amplifications of surface-enhanced Raman scattering (SERS) by microfluidic compact disk (CD)-based preconcentration method is accomplished for effective label-free bioassays and chemical detections. This is the first demonstration of the SERS-CD platform having capabilities of high-throughput microfluidic multifunctional on-chip biomedical devices. In order to achieve the preconcentration through the accumulation of biomolecules adsorbed on the SERS active site, we inject and dry biomolecular sample solution in the microfluidic channel prior to SERS detection and then repeat this cycle.

Project end date: 01/23/08