Jun-Chau Chien (Advisor)

Research Advised by Professor Jun-Chau Chien

Chien Group:  List of Projects | List of Researchers

An RFID-inspired One-step Packaged Multi-mode Bio- analyzer with Vacuum Microfluidics for Point-of-Care Diagnostics

Yan-Ting Hsiao
Ya-Chen (Justine) Tsai
Wei Foo
Hung-Yu Hou
Lily Li
Jun-Chau Chien
2025

This paper presents a fully wireless CMOS/microfluidics bioanalyzer for point-of-care use, addressing packaging complexity and external fluidic actuation. It integrates amperometric, pH, and temperature sensors with wireless power and 700MHz communication. The amperometric front-end achieves 0.24pArms noise at 100Hz with 129.8dB DR and consumes 2.5mW. The pH sensors use 20µm × 20µm Al2O3 membranes on ion-sensitive FETs. PDMS vacuum-actuated microfluidics and immunoassays are demonstrated.

Subtractive Nanofluidics in 65-nm CMOS Copper BEOL Achieve 100-nm Width

Alexander Di
Michael Pedowitz
Jun-Chau Chien
2026

This paper presents the first implementation of 100- nm-wide nanofluidics in a 65-nm CMOS chip using a one- step wet-etch to remove the copper routing from the back- end-of-line (BEOL) while maintaining transistor integrity through continuous monitoring of the IDS-VGS characteristics. Vertical fluidics are also successfully demonstrated by etching through 360 nm × 360 nm-sized vias. A non-destructive laser microscopy technique for imaging fluidic channels at a dimension below the visible- light wavelength is developed.

Keywords: CMOS, subtractive nanofluidics, microfluidics, BEOL...

Real-Time Monitoring of Trastuzumab Monoclonal Antibodies Using Electrochemical Aptamer-Based Sensors

Wei Foo
Xieshi Zhang
S. Maya Vanichakorntanes
Ya-Chen (Justine) Tsai
Jun-Chau Chien
2026

The real-time monitoring of trastuzumab (Tmab), a monoclonal antibody used for cancer treatment, is critical for personalized, response-guided dosing and improved biomanufacturing quality control. Currently, Tmab concentrations are quantified using immunoassays and mass spectrometry, but these platforms provide only discrete measurements and require extensive sample preparation. Surface-tethered electrochemical aptamer-based (E-AB) sensors provide a unique alternative because they operate without free-floating reagents, enable continuous measurements, and can be engineered to achieve high...

Kyeongho Eom

Postdoctoral Researcher
Electrical Engineering and Computer Sciences
Professor Jun-Chau Chien (Advisor)
PostDoc 2026 to present.

Kyeongho Eom received the B.S. and Ph.D. degrees in electrical engineering from Korea University, Seoul, South Korea, in 2020 and 2025, respectively.

From 2025 to 2026, he was a postdoctoral researcher at Korea University. Since 2026, he has been a postdoctoral researcher at the University of California, Berkeley, CA, USA. His current research interests include analog and mixed-signal IC design for wirelessly powered neural interfaces, retinal and visual prostheses, and electrochemical sensing and modulation.

Dr. Eom was a recipient of the Korean President’s Award (1st) in...

FlexCMOS: Single-die Flexible Electronics Enabled by XeF₂-etched SOI CMOS

Kyeongho Eom
2026
Fall 2026 BSAC Research Review Presentation View Presentation View Slides

Kelly Chang

Graduate Student Researcher
Electrical Engineering and Computer Sciences
Professor Jun-Chau Chien (Advisor)
Ph.D. 2030 (Anticipated)

Tianqi Lu

Postdoctoral Researcher
Electrical Engineering and Computer Sciences
Professor Jun-Chau Chien (Advisor)
PostDoc 2026 to present.

Tianqi Lu (Member, IEEE) received the Ph.D. degree in microelectronics from Delft University of Technology, Delft, The Netherlands, in 2026. He is currently a Postdoctoral Researcher with the Department of Electrical Engineering and Computer Sciences (EECS), University of California, Berkeley, CA, USA. His research interests include analog and mixed-signal integrated circuits for biomedical applications, biosensors, wearable and implantable devices, and next-generation power-management circuits. He received the ISSCC Student Research Preview Poster Award in 2026 and ISSCC Student...

Wan-Yi Lee

Graduate Student Researcher
Electrical Engineering and Computer Sciences
Professor Jun-Chau Chien (Advisor)
M.S, 2028 (Anticipated)

Wan-Yi Lee is currently pursuing an M.S. in EECS at UC Berkeley, following her undergraduate studies in Electrical Engineering at National Taiwan University. Her current research interests lie at the intersection of integrated circuits and bio-sensing technologies.

Sumeyye Seker

Postdoctoral Researcher
Electrical Engineering and Computer Sciences
Professor Jun-Chau Chien (Advisor)
PostDoc 2026 to present.

Sumeyye Seker earned her B.Sc. degree in Medical Engineering, complemented by international academic exchange experiences in Turkiye, Malaysia, Slovakia, and the United Kingdom. She then earned her M.S. degree from Imperial College London in 2021 and her Ph.D. in NanoEngineering from the University of California, San Diego, in 2026, where she worked under the supervision of Professor Joseph Wang. She is currently a Postdoctoral Researcher at the University of California, Berkeley.

Dr. Seker’s research interests include biosensors, wearable and flexible electronics, electrochemical...

Alexander Di

Graduate Student Researcher
Electrical Engineering and Computer Sciences
Professor Jun-Chau Chien (Advisor)
B.S. 2025, Ph.D. 2030 (Anticipated)

BSAC Spring 2026 Research Review Presenter