Jun-Chau Chien (Advisor)

Current quantum processor units (QPUs) have achieved over 1,000 qubits (e.g., IBM's Condor processor). However, scaling quantum platforms toward 1 million qubits demands breakthroughs in quantum hardware, connectivity, error correction, and system architecture. To address the scalability of quantum interconnects, Cryo-CMOS control and readout circuits have demonstrated efficacy in reducing wiring complexity, latency, and thermal loads. However, the CMOS circuits limit the active heat load to 1–2 mW/qubit, imposing a limit of approximately 1,000 qubits in state-of-the-art dilution...

Current clinical practice for detecting low-concentration molecular biomarkers requires sending samples to centralized labs, leading to high costs and delays (Fig. 20.3.1). Recent developments in molecular diagnostics thus aim to enable point-of-care (POC) detection directly at or near the patient's location [1]–[2]. The most successful POC technology to date is the paper-based lateral-flow assay (LFA) [3]–[4]. Examples include pregnancy tests that sense progesterone and SARS-CoV-2 rapid antigen tests. However, paper-based assays generally provide binary results or limited quantitative...