Liwei Lin (Advisor)

Access to affordable and user-friendly biosensors is crucial for advancing global healthcare. While lateral flow immunoassays have been the primary solution for decades, their limited sensitivity and suboptimal sample utilization present challenges. This project represents a systematic progression towards developing economically viable biosensors with heightened sensitivity, covering a range of diseases from viral infections to cancer. By integrating nanoplasmonics to induce visually perceptible signals and harnessing the coffee ring effect for protein pre-concentration, we achieved...

Ultrasonics has been realized as a nondestructive measurement method for a variety of applications, such as medical imaging, healthcare monitoring, structural testing, range finding, and motion sensing. Furthermore, high intensity ultrasound can be used in therapeutic treatments, such as lithotripsy for kidney stone comminution, hyperthermia for cancer therapy, high-intensity focused ultrasound (HIFU) for laparoscopic surgery and transcranial sonothrombolysis for brain stroke treatment. MEMS ultrasonic transducers are known to have several pronounced advantages over the conventional...

The next big thing, AR/VR, requires an immersive Human Machine Interface (HMI) in addition to visual and sound stimuli. Although skin is the biggest organ in the human body, very few efforts compared to visual and auditory senses have been done to develop a “sense of touch”. The mechanical stimulus to generate the touch sense by the embedded mechanoreceptors in the skin at different depths has been created in many ways as vibratory actuators, microneedles, etc. In this project, we are investigating to create haptic interface via radiation force generated by piezoelectric...