BSAC Seminar: Microplatforms for Cell Biomechanics Studies

November 17, 2009

Prof. Bill Tang

Biomedical Engineering, UC Irvine
BSAC PhD 1990
November 17, 2009 | 12:00 to 01:00 | 540 Cory Hall, DOP Center Conference Room
Host: Luke Lee

Cytoskeletons provide the mechanical properties of a cell and support the cell body with intricate connections to the extra-cellular matrix through focal adhesion complexes on the cell membrane. Recent research in cell biology has established that these mechanical structures play important roles in healthy cell functions such as growth, proliferation, migration, differentiation and embryogenesis, as well as diseases such as cancer metastasis, cardiovascular diseases, arthritis and immune dysfunction. This talk will cover the design, theory, computer modeling, fabrication and preliminary results of a microfabricated platform that leverages smart structures in the study of cell biomechanics. The ultimate goal is to create an automated chip-based, non-invasive, micro-sensor platform for rapid cell monitoring and diagnosis.

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Jonathan Candelaria
Dalene Schwartz Corey