Publications

Brain-controlled prostheses have the potential to improve the quality of life of a large num- ber of paralyzed persons by allowing them to control prosthetic limbs simply by thought. An essential requirement for natural use of such neural prostheses is that the user should be provided with somatosensory feedback from the artificial limb. This can be achieved by electrically stimulating small populations of neurons in the cortex; a process known as cor- tical microstimulation. This dissertation describes the development of novel technologies for experimental neuroscience and their use...

We present a post-processed 6.25mm2 0.18μm Complementary Metal Oxide Semiconductor (CMOS) platform that leverages the advantages of super-paramagnetic bead labeling to integrate on-chip the label separation and detection functionalities required for high sensitivity bio-assays. The surfaces of the CMOS chip and of the magnetic beads are functionalized with bio-chemicals complementary to a target analyte. In a sandwich capture format, the presence of the target analyte will strongly bind 4.5μm magnetic bead labels to the...

The micro total analysis system (uTAS) has seen great interest and advances since its definition over two decades ago. By harnessing the fabrication tools of the semiconductor industry and exploiting the unique physical phenomena that dominate at the micro- to nano-scale, these devices aim to address applications ranging from point-of-care diagnostics to pharmaceutical development. A truly versatile uTAS technology platform will enable reconfigurable, parallel, and high resolution analysis, processing, and sorting/purification. To this end, we present the concept of light-induced...

The ever increasing need for regional and global roaming together with continuous advances in wireless communication standards continue to push future transceivers towards an ability to support multi-mode operation with minimal increases in cost, hardware complexity, and power consumption. RF channel-select filter banks pose a particularly attractive method for achieving multiband reconfigurability, since they not only provide the needed front-end reconfigurability, but also allow for power efficient and versatile transceiver designs, e.g., software-defined radio. Such channel-select...