Michel M. Maharbiz (Advisor)

Research Advised by Professor Michel M. Maharbiz

Gabriel Lavella

Alumni
Professor Michel M. Maharbiz (Advisor)
PostDoc 2012

Taesung Kim

Alumni
Professor Michel M. Maharbiz (Advisor)
PostDoc 2009

Daniel Huang

Alumni
Professor Michel M. Maharbiz (Advisor)
PostDoc 2012

Timothy Hanson

Alumni
Professor Michel M. Maharbiz (Advisor)
PostDoc 2017

Maysamreza Chamanzar

Alumni
Professor Michel M. Maharbiz (Advisor)
PostDoc 2016

Tushar Bansal

Alumni
Professor Michel M. Maharbiz (Advisor)
PostDoc 2009

Nanoplasmonics-enabled On-Demand and Systematic Gene Regulation

Eunice Lee
Luke P. Lee
Michel M. Maharbiz
Tejal Desai
Han Lim
2010

In this dissertation, nanoplasmonic optical antennae are utilized as “nanoplasmonic gene switches” for on-demand and systematic gene regulation in living systems. The plasmon resonance of nanoplasmonic gene switches is specifically tuned to the near- infrared spectral region where cells and tissues are essentially transparent. Due to their extraordinarily large surface-to-volume ratio, nanoplasmonic gene switches are ideal carriers of interfering oligonucleotides, such as antisense DNA and short interfering RNA oligonucleotides (siRNA). Interfering oligonucleotides enable direct,...

Microengineered Platforms For Assessing Cell-Cell Communication and Single-Cell Influences on Adult Neural Stem Cell Fate

Sisi (Siyu) Chen
Michel M. Maharbiz
David V. Schaffer
Henk Roelink
Zev Gartner
2012

The signaling environment experienced by a single cell is highly dependent on its interactions with its neighbors, which may secrete locally acting factors or act via membrane bound receptor-ligand systems. Stem cells are particularly sensitive to these signals, which act in concert to regulate self-renewal and discrete transitions into distinct fates. In the case of the adult neural stem cell, decades of in vivo and in vitro work have illustrated specific roles for different types of niche cells and some of the molecular mediators...

High-Resolution μECoG: Design, Fabrication, and Applications

Peter Ledochowitsch
Michel M. Maharbiz
Jose M. Carmena
Robert T. Knight
Christoph E. Schreiner
2013

Since the early 1950s, electrocorticography (ECoG), the measurement of electrical po- tentials on the surface of the brain has become an invaluable tool in neurosurgery for the localization of epileptic foci before resection. The ECoG electrodes used in clinical practice are made in an archaic serial process that involves hand-soldering wires to a stiff, coarse grid of electrodes with a spatial resolution >1 cm, and a tangle of transcranial wires. In this thesis we report a modern microfabrication process based on photolithographic pat- terning of...

Engineering Collective Behaviors

Daniel Cohen
Michel M. Maharbiz
Tejal Desai
Evan Variano
2013

Much of the world consists of many small things, animate or inanimate, interacting with each other to produce something larger than, and different from themselves. Comprising murders of crows, armies of ants, schools of fish, dunes of sand, and various organs in your body, the collective behaviors of these systems embody a different approach to engineering than we currently employ. This thesis explores three examples where principles from collective behaviors are deployed as engineering tools. The first example presents how the collective phenomenon of ‘percolation’ can be leveraged...