Michel M. Maharbiz (Advisor)

Research Advised by Professor Michel M. Maharbiz

Transparent Micro-electrocorticography (μECoG) Arrays for Optogenetic Mapping of Surface Potentials

Brian Pepin

Michel M. Maharbiz

2013

Electrocorticography (ECoG) has been used for decades clinically to help localize epileptic seizures but has only recently come into vogue as a potentially useful imaging modality. This change has partially been driven by the development of new micro-electrocorticography (µECoG) arrays which take advantage of modern surface micromachining techniques to achieve extremely dense electrode arrays packed with tiny (less than500µm diameter) electrodes. As an imaging tool, µECoG may be improved by taking advantage of the transparent µECoG array technology developed at the University of...

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Dosimetry Dust: An Ultrasonic Backscatter Implantable Dosimetry Device

Stefanie Garcia

Michel M. Maharbiz

Kristofer S.J. Pister

2017

Proton beam therapy is a well-established medical procedure for treating certain kinds of cancer, and is uniquely suited for treatment of head, neck, and eye tumors. Despite the continuous improvements in medical physics treatment plan simulations, improper tissue irradiation can easily occur if there is a shift in the tumor and/or critical organs during the irradiation process. A fully implantable dosimeter for in vivo dose measurements can provide closed loop treatment feedback to a physician during radiation treatments, and assist in enabling full irradiation of a tumor. This work...

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BPN795: An Implantable Microsensor for Cancer Surveillance

Kyoungtae Lee

2021

We aim to create an implantable dosimeter for the Crocker Nuclear Laboratory’s proton beam therapy treatment. Currently, there is no closed loop solution to verify the dose treated to a specific in vivo location. By using ultrasound as a communication platform, we aim to enable real time in vivo dose readings to physicians. This can lead to better-localized irradiation treatment of cancer, and minimize irradiation to vital, healthy tissues. This technology could also be calibrated for specific military applications.

Project ended: 05/01/2021

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BPN894: Acoustically-Driven, Electrically-Controlled Microswimmer

Mauricio J. Bustamante

2021

Underwater self-powered micro-swimmers have several biomedical and environmental applications, such as drug delivery and pathogen elimination in water. Therefore, there is a need for propulsion mechanisms that operate well in the low Reynolds number regimen. We propose a mechanism that uses resonating water-air interfaces to generate underwater propulsion, and electrolysis as a control mechanism. This way, an external field can be used as a power source while control occurs at the device level. It is known that, when actuated by ultrasound waves near its resonance frequency, a bubble...