Luke P. Lee (Advisor)

SoonGweon Hong

Alumni
Professor Luke P. Lee (Advisor)
PostDoc 2019

Ebrahim Ghafar-Zadeh

Alumni
Professor Luke P. Lee (Advisor)
PostDoc 2011

Ivan Dimov

Alumni
Professor Luke P. Lee (Advisor)
PostDoc 2012

Inhee Choi

Alumni
Professor Luke P. Lee (Advisor)
PostDoc 2014

Yeonho Choi

Alumni
Professor Luke P. Lee (Advisor)
PostDoc 2010

Dukhyun Choi

Alumni
Professor Luke P. Lee (Advisor)
PostDoc 2008

Doyeon Bang

Alumni
Professor Luke P. Lee (Advisor)
PostDoc 2018

Integrated Nanoplasmonic Optical Microfluidics for Label-free Bioassays

Yir-Shyuan Wu
Luke P. Lee
Ming C. Wu
Steve Conolly
2009

Current cellular assays are limited to multi-well based cell culture samples, and the existing cellular protein detection methods are restricted to labeling the targeting molecules with fluorescent dyes or other reporters. Microfluidic cell culture technology can provide precise and physiologically relevant microenvironment control to improve the quality of cell based assays. Nanoplasmonic optical probes enable the label-free detection of cellular protein with high temporal and spatial resolution. The goal of this dissertation is to develop and integrate real-time label-free...

Nanoplasmonics-enabled On-Demand and Systematic Gene Regulation

Eunice Lee
Luke P. Lee
Michel M. Maharbiz
Tejal Desai
Han Lim
2010

In this dissertation, nanoplasmonic optical antennae are utilized as “nanoplasmonic gene switches” for on-demand and systematic gene regulation in living systems. The plasmon resonance of nanoplasmonic gene switches is specifically tuned to the near- infrared spectral region where cells and tissues are essentially transparent. Due to their extraordinarily large surface-to-volume ratio, nanoplasmonic gene switches are ideal carriers of interfering oligonucleotides, such as antisense DNA and short interfering RNA oligonucleotides (siRNA). Interfering oligonucleotides enable direct,...

Biologically-inspired Microfluidic Platforms and Aptamer-based Nanobiosensors

Hansang Cho
Luke P. Lee
Dorian Liepmann
Ming C. Wu
John Kurhanewicz
2010

Recent advances in micro/nano- technologies have shown high potentials in the field of quantitative biology, biomedical science, and analytical chemistry. However, micro/nano fluidics still requires multi-layered structures, complex plumbing/tubing, and external equipments for large-scale applications and nanotechnology-based sensors demand high cost. Interestingly, nature has much simpler and more effective solutions. The goal of this dissertation is to develop novel microfluidic platforms and nanobiosensors inspired by biological systems.

In this dissertation, I...