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BPN818: Fully-Integrated Wearable Sensor Arrays for Multiplexed In Situ Perspiration Analysis

Project ID BPN818
Start Date Mon 2016-Jan-25 13:30:01
Last Updated Mon 2017-Mar-13 09:10:40
Abstract Wearable sensor technologies play a significant role in realizing personalized medicine by continuously monitoring an individualís health state. In particular, human sweat is an excellent candidate for these technologies as it contains physiologically rich information and serves as a target for non-invasive monitoring. Given the complexity of sweat secretion, simultaneous and multiplexed screening of target biomarkers is critical, and full system integration to ensure the accuracy of measurements is necessary. A mechanically flexible and fully-integrated perspiration analysis system is developed to simultaneously and selectively measure sweat metabolites (e.g. glucose and lactate) and electrolytes (e.g. sodium, potassium, calcium and pH), as well as skin temperature to calibrate the sensors' response. On-body heavy metal analysis in perspiration is also presented. This work bridges the technological gap between signal transduction, conditioning, processing and wireless transmission in wearable biosensors by merging plastic-based sensors that interface with the skin, and silicon integrated circuits consolidated on a flexible circuit board for complex signal processing. This wearable system can be used to measure detailed sweat profiles of human subjects engaged in prolonged indoor and outdoor physical activities, and assess their physiological states in real-time. The platform enables wearable technologies to perform a wide range of personalized diagnostic and physiological monitoring applications.
Status Continuing
Funding Source BSAC Member Fees
IAB Research Area Physical Sensors & Devices
Researcher(s) Hnin Y.Y. Nyein, Li-Chia Tai, Mallika Bariya, Wei Gao
Advisor(s) Ali Javey
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