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BPN706: Single-Layer Microfluidic Gain Valves via Optofluidic Lithography

Project ID BPN706
Website
Start Date Tue 2013-Jan-29 20:27:28
Last Updated Wed 2014-Aug-13 14:14:39
Abstract This project aims to create single-layer microfluidic gain valves for use in microfluidic devices. Autonomous microfluidic devices are essential for the long-term development of versatile biological and chemical platforms; however, the challenges of creating effective control mechanisms e.g., the need for variable pressure sources, signal degradation in cascaded devices, and multi-stage manufacture methods have proven considerable. Using in situ optofluidic lithography, we develop a single-layer pressure-based valve system with a static gain greater than unity. We will demonstrate the device in several microfluidic circuits, including logic gates and amplifiers. These pressure gain-based systems will enable microfluidic devices with a wide range of applications, such as flow rectifiers, oscillators, and high-precision pressure measurements. Due to ease of manufacture and design flexibility, this valve design could have widespread Lab-on- a-Chip applications by enabling self-regulation of microfluidic devices.
Status Continuing
Funding Source Fellowship
IAB Research Area Microfluidics
Researcher(s) Casey C. Glick, Christopher Deeble, Ki Tae Wolf, Vishnu Jayaprakash
Advisor(s) Liwei Lin
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